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If you truly are comfortable deleting ALL of your backups, then yes you can safely do so within Windows the same way you'd delete any other files. The reason for the advice about using Reflect is that it prevents you from (for example) deleting a single Incremental backup file in the middle of a set, or deleting a Full backup from which Differentials and/or Incrementals had been created. Windows Explorer would of course have no problem deleting such files, but such deletions would immediately invalidate subsequent backups in the set. If you tried to delete such files within Reflect, it would immediately select the subsequent backups in the set for deletion to show you the impact of your initial selection and of course to avoid keeping useless data on your hard drive just taking up space. However, I always caution against deleting all backups because unless you have other backups stored elsewhere, technically there's a risk window between the time you delete those backups and the time you successfully capture a new one. If your hard drive got fried in that window, you'd be left with no primary copy of your data and no backups, at least no backups that would be easily and reliably retrievable.
If you want to delete backups within Reflect, go to the Restore tab, then select the Image or File and Folder Backups tab as appropriate, and your backups should be listed. If they're not, click "Folders to Search" and add the location of your backups. Then you'll find the Delete File option under the Other Actions button, which will bring up a window that allows you to select additional backups to delete them in one fell swoop.