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It sounds like you have an image captured from a Windows PC and you want to either a) boot that image as a VM on your Mac, using something like VMware or Parallels, or b) mount the image as a virtual drive to extract files from it. You can't do either one. Reflect does not run in any capacity on Mac OS, and its image file format is proprietary. I'm not aware of any third-party tools that run on Mac OS or anywhere else that know how to interpret Reflect's image files so that they can either be mounted accessed as virtual drives or fed to a VM hypervisor to be used as a virtual disk of a VM.
In terms of restoring your image onto a USB drive, unlike Mac OS, Windows does not support booting from a USB device (except for installations specifically prepared as a Windows To Go environment from the beginning, but that's only available to enterprises and wouldn't apply here anyway), so you can't simply restore an image from a Windows PC onto a USB hard drive and then boot from it while it's still connected via USB. And even if that weren't an issue, there are certainly other complications you would likely face trying to get a Windows environment originally created on another PC to boot on a Mac. And even after all of that, your Windows environment would fall out of its activated status because you were now running it on completely different hardware.