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Macrium is definitely still in business, not sure what's going on with the site. Maybe a maintenance window or temporary outage?
Anyhow, in terms of your error, check your Scheduled Backups tab all the way to the right and see if there are any jobs listed there that reference this file. If so, you should be able to right-click them and delete them. If you don't find anything there, you'll probably have to open Windows Task Scheduler directly and see if you can find any scheduled tasks that call Reflect and specify this missing definition file.