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While not particularly common, the need to do so can occasionally arise, & currently the interface requires you to select partition(s) as the source for a cloning operation, yet you may need to clone an "entire drive" to an identical one where no partitions show on the source.
Some situations where you might want to do this could be:
A drive encrypted using dm-crypt plain or LUKS with detached header.
A drive from a Drobo disk pack (support occasionally suggest a block level clone to a new drive).
A drive with a damaged partition table, where you wish to attempt recovery on a clone without risk to the original.
A working drive from a RAID 5 array showing SMART notifications, where you'd rather shut down the array & clone the drive than endure a long rebuild replacing it live, something that can be risky.
This would only need to be available in the advanced options when "Forensic mode" was selected (intelligent sector copy off) as it makes no sense as an option otherwise.
Currently you have to either use dd from Linux, or hunt down some other Windows software which is capable of this clone operation.